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Nanyang Technological University

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Through lab experiments using human cells grown in a dish, the NTU scientists found that ASO-1 potently reduced TYK2 levels over a sustained period and inhibited immune signalling pathways that have been associated with autoimmune disorders. With a recently published UK-led study linking high TYK2 expression to severe COVID-19, ASO-1 could be a therapeutic agent worth investigating further, said the scientists.

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NTU Singapore

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