Image 2 (IMAGE) Nanyang Technological University Caption Through lab experiments using human cells grown in a dish, the NTU scientists found that ASO-1 potently reduced TYK2 levels over a sustained period and inhibited immune signalling pathways that have been associated with autoimmune disorders. With a recently published UK-led study linking high TYK2 expression to severe COVID-19, ASO-1 could be a therapeutic agent worth investigating further, said the scientists. Credit NTU Singapore Usage Restrictions Use with mandatory credit License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.