NUS Scientists Discover the 'Switch' that Makes Breast Cancer Cells Aggressive (IMAGE)
Caption
A study by scientists from the Cancer Science Institute of Singapore at the National University of Singapore (NUS) and NUS Yong Loo Lin School of Medicine showed that a less aggressive tumor when artificially made to increase its Manganese Superoxide Dismutase (MnSOD) levels, turns into a more aggressive tumor. The nucleus of the cells in both images are in blue while the parts in red that became more abundant (Image 2) shows the presence of a protein called Vimentin. Vimentin is often used as a marker of mesenchymal (aggressive) cells or cells undergoing an epithelial-to-mesenchymal transition (EMT), a term used to describe the process whereby a tumour converts to a different form capable of moving to distal organs in the body.
Credit
National University of Singapore
Usage Restrictions
Please note that the caption for photos 1 & 2 are linked.
License
Licensed content