Figure 2 (IMAGE)
Caption
Reactions in the cell nucleus (a): The RNA is depicted in red, with the DNA shown as black double lines and a linking molecule in dark blue. The light blue circles stand for proteins. The black dot is a molecule that allows to single out the DNA-RNA hybrid in solution. Explanations are provided in the text. Reactions in solution (b): protein removal, second strand synthesis, clipping to predetermined size, addition of sequences used for recognition, and sequencing.
Credit
Alessandro Bonetti et al./<em>Nature Communications</em>
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