Inner Membrane (IMAGE) Penn State Caption The inner membrane of each mitochondrion contains distinctive folds known as cristae. In a normal mitochondrion (left) these folds fill the interior, but these folds are lost in damaged or dysfunctional mitochondria (right). Dozens of rare diseases have been shown to result from this type of mitochondrial dysfunction. Several others -- including Alzheimer disease, autism, cancer, cardiovascular disease, Parkinson disease, and type 2 diabetes -- are suspected to involve the mitochondria. Credit Gary Carlson Usage Restrictions The image credit must be published along with the image. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.