Comparison of Heart Functions in Different Experimental Groups (IMAGE)

City University of Hong Kong

Comparison of Heart Functions in Different Experimental Groups

Caption

This graph shows the comparison of heart functions in different experimental groups: (i) healthy heart (Sham) ; (ii) untreated myocardial infarction control (CON); (iii) human bone marrow derived-MSCs (BM-MSC) only, (iv) genetically engineered MSCs only (HGF-eMSC), and (v) BM-MSC+ HGF-eMSC mixture. The mixture group shows the best result in left ventricular ejection fraction (LVEF) among the groups using MSCs, which means an enhancement in cardiac function. For example, after 8 weeks, the mixture group shows about 50% of left ventricular ejection fraction, while the untreated control group only shows nearly 32%.

Credit

Science Advances; 10.1126/sciadv.aay6994

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