Intracellular pH Sensing (IMAGE)
Caption
Fluorescent micrographs collected from COS-1 cells co-injected with 550 nm emitting QD-dopamine conjugates and red FLX internal standard nanospheres in buffer at pH 6.5. The growth media was switched to pH 11.5 supplemented with the drug Nystatin and micrographs were captured at the indicated time intervals from both the QD and FLX emission channels. Merged images are shown in the bottom row and pH values extracted at each time interval are shown below.
Credit
Naval Research Laboratory/Scripps Research Institute
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