Alzheimer's Protein Structure (IMAGE)

Vanderbilt University Medical Center

Alzheimer's Protein Structure

Caption

Vanderbilt Center for Structural Biology investigators determined the structure of the C99 protein (shown in green and blue), which participates in triggering Alzheimer's disease. Their discovery that C99 binds to cholesterol (shown in black, white and red) suggests a mechanism for cholesterol's recognized role in promoting the memory-robbing disease and may lead to new therapeutics.

Credit

Charles Sanders and colleagues/Vanderbilt University

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