Optogenetic Photosensitizer Allows for Targeted Cell Manipulation (IMAGE)

Carnegie Mellon University

Optogenetic Photosensitizer Allows for Targeted Cell Manipulation

Caption

Zebrafish larvae expressing FAP in the heart are treated with a normal fluorogen (left) or the targeted, activated photosensitizer (TAPS-right), then exposed to light and followed for 3 days. Only the TAPS-treated fish show defects associated with loss of cardiac function after photoablation, including loss of cardiac tissues (blue), cardiac edema, and other developmental defects.

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Carnegie Mellon MBIC

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Credit: Carnegie Mellon MBIC

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