Regenstrief Study (IMAGE) Regenstrief Institute Caption Regenstrief researchers are conducting 1st clinical trial to investigate whether there is a cause and effect relationship (rather than simply a link) between anticholinergics (a class of drugs frequently taken by older adults) and cognitive decline. Credit Regenstrief Institute Usage Restrictions Credit to Regenstrief Institute License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.