Mutational Analysis of Protein Stability (IMAGE)

University of Washington School of Medicine/UW Medicine

Mutational Analysis of Protein Stability

Caption

This image is from a comprehensive mutational analysis of stability in designed and natural proteins. The average change in stability due to mutating each position in 13 designed proteins is depicted on the design model structures. Yellow indicates positions where mutations are most destabilizing; positions where there is little effect are blue

Credit

UW Medicine Institute for Protein Design

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