ATRX and Chromosome Stability (IMAGE) University of Georgia Caption ATRX is required to maintain chromosome stability. Genome-wide analysis by spectral karyotyping reveals that loss of ATRX function in mouse cells results in centromeric breaks and chromosome translocations. Insets illustrate the translocation of a fragment of chromosome 16 into the centromeric region of chromosome 17. Credit University of Georgia Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.