Screening the Human Kinome for Breast Cancer Drug Resistance Clues (IMAGE)

Arizona State University

Screening the Human Kinome for Breast Cancer Drug Resistance Clues

Caption

Dr. Joshua LaBaer's Biodesign Institute team used a well-established cell model for breast cancer along with the extensive collection of fully sequenced human genes, the team performed the largest genetic screen of its kind -- testing the ability of 500 regulatory proteins, called kinases, that have been implicated in tumor growth and drug resistance.

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Biodesign Institute, Arizona State University

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