此研究中提出的新型冠状病毒重症感染的免疫学机制 (IMAGE) Kumamoto University Caption 新型冠状病毒感染的轻度和重度病例之间的主要区别被认为是T细胞针对病毒产生极端活性化。轻度病例情况下,转录因子Foxp3的诱导可阻止T细胞活性化。另一方面,在重症病例情况下,不会诱导Foxp3使T细胞活性化失控,从而引起严重的免疫反应 Credit Associate Professor Masahiro Ono Usage Restrictions <p>Adapted from Fig. 5 of <a href="https://www.frontiersin.org/articles/10.3389/fimmu.2020.589380/full">Kalfaoglu, B. et al., Frontiers in Immunology, 2020</a>. </p> <p>This image is made available under the terms of <a href="https://creativecommons.org/licenses/by/4.0/">CC by 4.0</a>. Any further distribution of this work must follow the terms of this license. </p> License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.