Throwing a Wrench in Cancer's Gears (IMAGE)

Cold Spring Harbor Laboratory

Throwing a Wrench in Cancer's Gears

Caption

By generating a small protein fragment, or peptide (green square), shaped exactly like the surface where MYB, a cancer promoter, typically binds to a gene co-activator complex (green segment in long rectangle labeled TAF4, above), researchers prevent MYB from activating gene expression and promoting leukemia.

Credit

Vakoc Lab, CSHL

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