Supressing FER Reduces Metastasis (IMAGE)

Cold Spring Harbor Laboratory

Supressing FER Reduces Metastasis

Caption

Experiments in mice showed that FER helps to promote metastasis in ovarian cancer. Three mice with similar primary ovarian tumors are shown prior to surgery (top row) and following surgery (middle and bottom rows). A metastasis of the primary tumor appears in a lung of the mouse in the left column. FER was active in this mouse. The other two mice, in which FER has been inactivated genetically, remain cancer-free at the same time point following removal of the primary tumor.

Credit

Tonks Lab, CSHL/Genes&Development

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