Diseased Retinal Cells are Treated with Gene Therapy (IMAGE)

Columbia University Irving Medical Center

Diseased Retinal Cells are Treated with Gene Therapy

Caption

In normal, or wild-type, retinal cells (left), the protein actin forms the cell's cytoskeleton, creating an internal support structure that looks like a series of connected hexagons. In cells with MFRP mutations (center), this structure fails to form, compromising cellular function. When diseased retinal cells are treated with gene therapy to insert normal copies of MFRP (right), the cell's cytoskeleton and function are restored.

Credit

Lab of Stephen H. Tsang, M.D., Ph.D./Columbia University Medical Center.

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