Pembrolizumab Image (IMAGE)

Fred Hutchinson Cancer Center

Pembrolizumab Image

Caption

Multispectral immunofluorescence shows the interface between Merkel cell tumor cells (orange) and host immune cells (yellow marks CD8+ lymphocytes, red marks CD68+ macrophages). Cell-surface PD-L1 expression (green) is observed on macrophages, lymphocytes and tumor cells, adjacent to PD-1 expression (white) on lymphocytes.

Credit

Courtesy of Janis Taube, Johns Hopkins.

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