Kenneth Anderson, M.D., Dana-Farber Cancer Institute (IMAGE)

Dana-Farber Cancer Institute

Kenneth Anderson, M.D., Dana-Farber Cancer Institute

Caption

Kenneth Anderson, M.D., and his colleagues at Dana-Farber determined that P5091, a small molecule inhibitor of USP7 decreases the level of a cancer-promoting protein called HDM2, which has the effect of bolstering p53 and p21, a gene that suppresses tumor cell growth. The result is that the myeloma cells stopped growing and began to die.

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Sam Ogden

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