The therapeutic effects of AD-MSC-γ-sEVs (IMAGE) Niigata University Caption The AD-MSC-γ-sEVs effectively downregulate pro-inflammatory (IL-6, Tnf-a, Mcp-1, and Inos) and induce anti-inflammatory (iL-10, Ym-1, Fizz-1, Cd206) macrophage responses and in vitro. Credit Niigata University Usage Restrictions The image may only be used with appropriate caption or credit. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.