PfHAD1 Protein (IMAGE)

WashU Medicine

PfHAD1 Protein

Caption

Researchers have uncovered a way the malaria parasite becomes resistant to an investigational drug. The discovery, at Washington University School of Medicine in St. Louis, also is relevant for other infectious diseases including bacterial infections and tuberculosis. The research team defined the crystal structure of the PfHAD1 protein, above. When PfHAD1 is dysfunctional, the malaria parasite is resistant to fosmidomycin, an antibiotic in clinical trials for the treatment of malaria.

Credit

Niraj H. Tolia

Usage Restrictions

None

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.