Viral Infection Cycle (IMAGE)

Michigan Technological University

Viral Infection Cycle

Caption

1. Porcine parvovirus (PPV) infects a pig kidney cell (PK-13). 2. PPV attaches to PK-13 using its outer layer of proteins (capsid), which can be detected in a microfluidics device. 3. The viral RNA hijacks the inner machinery of the cell to make more viruses. 4. The antiviral osmolyte glycine likely interrupts capsid formation. 5. If uninterrupted, viral replicas burst through the cell membrane. 6. There is a shift in the electrical signal if glycine is present that is different from a regular infected cell.

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Phil Mcleod/Michigan Tech

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