Mammalian Cannabinoid Receptors (IMAGE) UT Southwestern Medical Center Caption The mammalian cannabinoid receptors (CB1 and CB2) sense endogenous endocannabinoids and plant and synthetic cannabinoids to engender a response in the host that leads to decreased inflammation, intestinal motility and secretion, and increased appetite. Mammalian endocannabinoids are also sensed by a bacterial cannabinoid receptor to decrease virulence of enteric pathogens. Credit UT Southwestern Medical Center Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.