Misfolded TDP-43 Proteins in Neurons of Brain Tissue (IMAGE)

University of Pennsylvania School of Medicine

Misfolded TDP-43 Proteins in Neurons of Brain Tissue

Caption

The identification of misfolded TDP-43 proteins in neurons of brain tissue (brown structures indicated by arrows) was a criterion for entry into this genome-wide study. The homogeneity of the pathologically-defined cohort is felt to be a major reason for the study's success.

Credit

Felix Geser, M.D., Ph.D., University of Pennsylvania School of Medicine

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