Structural Model of A-kinase Anchoring Protein 18 A protein Kinase A (VIDEO)

University of Washington School of Medicine/UW Medicine

Caption

This is a structural model of the enzyme A-kinase anchoring protein A protein kinase A, or AKAP18-PKA, as determined by single particle electron microscopy. This is the structure studied in the June 23, 2017, Science paper "Local protein kinase A action proceeds through intact holoenzymes.

Credit

Donelson Smith, Steve Reichow, Tamir Gonen and John Scott at UW Medicine, Seattle

Usage Restrictions

For use by news media covering research by Donelson Smith and John Scott at UW Medicine

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.