Role of TPX2 in Promoting Branching of Microtubules (VIDEO)

Princeton University

Caption

TPX2 behaves like a liquid in promoting branching microtubule nucleation. The protein TPX2 increases in concentration from left to right in the video. In the experiment, new microtubules formed when when TPX2 condensed with tubulin into liquid-like droplets.

Credit

Matthew King, Sabine Petry, Princeton University

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Matthew King, Sabine Petry, Princeton University

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