Concentrate Not Aggregate (IMAGE) Brown University Caption New research explains how the protein TDP43 normally concentrates into droplets and how ALS-related mutations disrupt that, leading to them to form more problematic aggregates that afflict cells. Credit Gül Zerze, Lehigh University Usage Restrictions with credit License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.