Cell-Entering Molecules Detect Activity of Proliferating Cell Nuclear Antigen (IMAGE)

University of Texas at Austin, Texas Advanced Computing Center

Cell-Entering Molecules Detect Activity of Proliferating Cell Nuclear Antigen

Caption

Proliferating Cell Nuclear Antigen (PCNA) is a key protein in DNA replication and repair. During the DNA synthesis phase (S-phase) PCNA is recruited to sub-nuclear sites of DNA replication forming distinctive patterns over time that characterize different S-phase stages. Simulations on TACC's Stampede supercomputer helped researchers understand these processes.

Credit

Henry Herce

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