Neutrophils in Pancreatic Cancer (IMAGE)
Caption
Fewer neutrophils lead to less inflammation in pancreatic tumors. In this photomicrograph of pancreatic tumor specimens taken from mice, neutrophils are shown in red and all other cells in blue. The image on the left shows a tumor formed by p63-positive pancreatic cancer cells and the image on the right shows the same pancreatic cancer cells but where the researchers used a genetic technique, CRISPR, to prevent cells from expressing p63. Note that there are far fewer neutrophils in the p63-negative tumor (right). Specimens were stained by immunofluorescence.
Credit
Vakoc lab/CSHL, 2020
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