TRPV3 Mutation (IMAGE) Columbia University Irving Medical Center Caption This is an image of human TRPV3 in the closed and open states viewed from outside the cell. Location of the region (N647) that is mutated in mammoths is highlighted. Credit Image of human TRPV3 in the closed and open states Alexander Sobolevsky / CUIMC Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.