Immunohistochemical Analysis (IMAGE) Hokkaido University Caption This is immunohistochemical analysis showing expression of PGE2 (left) and PD-L1 (right) in the ileal mucosa of a cow with Johne's disease. Credit Sajiki Y., et al., <i>Infection and Immunity</i>, February 26, 2018. Usage Restrictions This image is copyrighted and can be used for reporting this press release if properly credited. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.