Fragile X Memory-Sensory Neuron Connections (IMAGE)
Caption
Electron micrographs comparing the memory centers in the brains of normal and Fragile X syndrome flies illustrate the subtle effects of the syndrome on sensory neuron development. Sensory information enters the memory center through the ACT (antennocerebral tract; yellow-green), where sensory neurons make contact with the memory storage Kenyon Cells (KCs; light brown) within a region called the mushroom body (MB calyx; blue-green). The overgrown connections in the calyx and misshapen Kenyon cells indicate faulty development of the olfactory sensory circuit in the Fragile X brain.
Credit
Caleb Doll, Broadie Laboratory, Vanderbilt University
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