Dr Tracy Putoczki (Left) and Dr Lorraine O'Reilly, Walter and Eliza Hall Institute (IMAGE)

Walter and Eliza Hall Institute

Dr Tracy Putoczki (Left) and Dr Lorraine O'Reilly, Walter and Eliza Hall Institute

Caption

Researchers have made the surprise discovery that the 'odd one out' in a family of proteins known to drive cancer development is instead critical for preventing stomach cancers. The research team from the Walter and Eliza Hall Institute in Melbourne, Australia, showed switching off a gene called NF-κB1 caused spontaneous development of stomach cancers, driven by chronic inflammation. The study also revealed that immunotherapy may prove to be a significant tool for treating stomach cancers that are driven by runaway inflammation, warranting further investigation.

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Walter and Eliza Hall Institute

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