Switching Side in Cancer (2 of 2) (IMAGE)

Cold Spring Harbor Laboratory

Switching Side in Cancer (2 of 2)

Caption

The protein p53-psi, a variant of the well-known anti-cancer guardian protein p53, can reprogram cells to "switch sides" and acquire pro-metastatic features. Two types of cells that don't naturally express p53-psi (LEFT panel) exhibit changes in shape (RIGHT panel) characteristic of the transition to metastasis when they are made to express p53-psi.

Credit

Sordella lab, Cold Spring Harbor Laboratory

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