Dr. David Mangelsdorf (IMAGE) UT Southwestern Medical Center Caption Researchers led by Dr. David Mangelsdorf, chairman of pharmacology, helped create the first "encyclopedia" of an entire superfamily of nuclear receptors - proteins that turn genes on and off throughout the body - and discovered that certain receptors form networks and interact to regulate disease states and physiology in two main areas, reproduction and nutrient metabolism. Credit Credit Line: UT Southwestern Medical Center Usage Restrictions Credit must be given to the creator. License CC BY Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.