Three Major Findings Obtained from DROSHA fCLIP-seq Experiments (IMAGE)

Institute for Basic Science

Three Major Findings Obtained from DROSHA fCLIP-seq Experiments

Caption

The endings of some miRNAs were modified after DROSHA cleavage. Some pri-miRNA were processed at multiple sites (alternative processing). Moreover, beyond pri-miRNA, numerous other RNA substrates (noncanonical substrates) were found to be cleaved by DROSHA.

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