Illustration of the New fCLIP-seq Method to Study What and Where DROSHA is Cleaving Directly From th (IMAGE)

Institute for Basic Science

Illustration of the New fCLIP-seq Method to Study What and Where DROSHA is Cleaving Directly From th

Caption

IBS scientists studied DROSHA's (pink) cleavage points (triangles) on pri-miRNA (green-orange-violet lines). The formaldehyde treatment forms a cross-link between the RNA products and the DROSHA, so it is possible to sequence and read the attached RNA products.

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IBS

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