Damaged DNA (IMAGE)

Johns Hopkins Medicine

Damaged DNA

Caption

Microscopic images of a breast cancer cell with DNA damage. Left, six hours after treatment with either the epigenetic agent alone or the PARP inhibitor alone. Right, six hours after treatment with both the epigenetic drug and PARP inhibitor. Yellow staining shows trapping of the PARP enzyme at a site of DNA damage.

Credit

Stephen B. Baylin, M.D. and Feyruz V. Rassool, Ph.D.

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