Research Strategy for Identifying Cyclic Peptides that Facilitate Small Intestinal Absorption (IMAGE)

Kumamoto University

Research Strategy for Identifying Cyclic Peptides that Facilitate Small Intestinal Absorption

Caption

Orally administered biopharmaceuticals must permeate human small intestinal epithelial cells. This may be done by identifying innovative cyclic peptides that facilitate small intestinal absorption of phage macromolecules that are larger than biopharmaceuticals. (Reprinted from the Journal of Controlled Release, 262, Shunsuke Yamaguchi, Shingo Ito, Mio Kurogi-Hirayama, Sumio Ohtsuki, Identification of cyclic peptides for facilitation of transcellular transport of phages across intestinal epithelium in vitro and in vivo, 232-238, 2017 with permission from Elsevier.)

Credit

Professor Sumio Ohtsuki

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