Cellular Senescence (IMAGE)

DOE/Lawrence Berkeley National Laboratory

Cellular Senescence

Caption

This trio of images show cancer cells that are normally non-aggressive and slow growing. The top image shows the cells in their typical state. In the middle image, the cells have lost the p53 tumor suppressor gene and are dividing much more aggressively. Cells in the final image have acquired the RAS oncogene and have started invading surrounding tissue.

Credit

(image courtesy of Judith Campisi)

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