Structure of Pre-miRNA/shRNAs (IMAGE) Hong Kong University of Science and Technology Caption Pre-miRNA/shRNA is illustrated by a Cactus. The branch represents the single-nucleotide bulge. Two flowers indicate the double cleavages of DICER. The roots show 5' and 3'-end of RNAs. Credit Choco Nguyen Usage Restrictions N/A License Original content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.