Visual abstract (IMAGE) Tokyo Medical and Dental University Caption Factor Xa–PAR2 signaling promotes atherogenesis by accelerating inflammasome activities through the suppression of macrophage autophagy. Credit Department of Cardiovascular Medicine, TMDU Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.