(IMAGE) Tokyo Medical and Dental University Caption Muscle fiber necroptosis and subsequent release of HMGB1 aggravate inflammation in PM. Credit Department of Rheumatology, TMDU Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.