Lisa A. Carey, MD, ScM, FASCO (IMAGE) UNC Lineberger Comprehensive Cancer Center Caption “We saw changes in biology in about 30% of patients, including loss of immune activation, especially in liver and brain metastases. Many of these changes occurred through mechanisms that can be reversed or treated. For this reason, we are very excited about the potential for improved treatment of metastatic disease, or even prevention of metastases themselves, based on this effort.” Credit UNC Lineberger Comprehensive Cancer Center Usage Restrictions None License Original content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.