End-stabilization by CAMSAP3 (IMAGE) School of Science, The University of Tokyo Caption A CAMSAP3 molecule is first recruited to the microtubule end via an “end-detector” region in the protein, and then, D2 expands the microtubule. The expanded microtubule region promotes further CAMSAP3 binding as D2 can both detect and attach to the expanded microtubules. The positive feedback loop leads to the accumulation of CAMSAP3 around the microtubule ends. Credit Liu and Shima et al 2023 Usage Restrictions Credit must be given to the creator. License CC BY Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.