図2. BTBR/Rマウスのコピー数多型解析と遺伝子発現解析 (IMAGE) Kobe University Caption a-c : ゲノム上に存在する内在性レトロウイルス遺伝子を含む反復配列のコピー数多型の比率。 d, e : 反復配列の遺伝子発現量の解析 BTBRマウスでは内在性レトロウイルス遺伝子であるERVのコピー数がB6よりも多く存在し、その一部は活性化が認められた。 Credit Lin, CW., Ellegood, J., Tamada, K. et al. An old model with new insights: endogenous retroviruses drive the evolvement toward ASD susceptibility and hijack transcription machinery during development. Mol Psychiatry (2023). Usage Restrictions Credit must be given to the creator. License CC BY Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.