News Release

Aldosterone synthase inhibition with lorundrostat for uncontrolled hypertension


Peer-Reviewed Publication

JAMA Network

About The Study: Among individuals with uncontrolled hypertension in this randomized clinical trial that included 200 participants, use of lorundrostat was effective at lowering blood pressure compared with placebo, which will require further confirmatory studies.

Authors: Steven E. Nissen, M.D., of the Cleveland Clinic Foundation, is the corresponding author.

To access the embargoed study: Visit our For The Media website at this link


Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Media advisory: This study is being released to coincide with presentation at the AHA Hypertension Scientific Sessions 2023.

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