News Release

Premenstrual disorders, timing of menopause, and severity of vasomotor symptoms

JAMA Network Open

Peer-Reviewed Publication

JAMA Network

About The Study: In this study of 3,635 female participants in the U.S., premenstrual disorders (PMDs) were associated with increased risks of early menopause and moderate or severe vasomotor symptoms (VMS). PMDs may be indicative of underlying physiology linked to early menopause and VMS, suggesting a phenotype observable during the reproductive years that may allow clinicians to target women at risk of earlier menopause and subsequent health risks later in the life course.

Authors: Yihui Yang, M.P.H., and Donghao Lu, M.D., Ph.D., of the Karolinska Institutet in Stockholm, Sweden are the corresponding authors.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi: 10.1001/jamanetworkopen.2023.34545)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.


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