News Release

Early metformin in gestational diabetes

JAMA

Peer-Reviewed Publication

JAMA Network

About The Study: In this randomized clinical trial, early treatment with metformin was not superior to placebo for the composite primary outcome of insulin initiation or a fasting glucose level of 5.1 mmol/L or greater at gestation weeks 32 or 38. Prespecified secondary outcome data support further investigation of metformin in larger clinical trials. 

Authors: Fidelma Dunne, Ph.D., of the University of Galway in Galway, Ireland, is the corresponding author.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jama.2023.19869)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Media advisory: This study is being released to coincide with presentation at the European Association for the Study of Diabetes Annual Meeting 2023.

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