About The Study: Among 2,511 adults hospitalized with acute infection, treatment with the antibiotic piperacillin-tazobactam did not increase the incidence of acute kidney injury or death in this randomized clinical trial. Treatment with the antibiotic cefepime resulted in more neurological dysfunction.
Authors: Edward T. Qian, M.D., M.Sc., of Vanderbilt University Medical Center in Nashville, is the corresponding author.
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(doi:10.1001/jama.2023.20583)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Media advisory: This study is being released to coincide with presentation at IDWeek 2023.
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Journal
JAMA