News Release

Metformin cessation and dementia incidence

JAMA Network Open

Peer-Reviewed Publication

JAMA Network

About The Study: Terminating metformin treatment was associated with increased dementia incidence in this study of 12,000 early terminators and 29,000 routine users of metformin. This finding may have important implications for clinical treatment of adults with diabetes and provides additional evidence that metformin is associated with reduced dementia risk. 

Authors: Sarah F. Ackley, Ph.D., of Boston University, Boston, is the corresponding author. 

To access the embargoed study: Visit our For The Media website at this link 


Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

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